Atropine

* Atropine Injection Veterinary is a muscle relaxant and anti-spasm used to treat poisoning with organic phosphorus compounds...

Generic Name:

Atropine Sulfate

Dosage Form:

[Injection]

Group:

Antitoxic

Packages:

50, 100ml

Mode of action or general info:

Atropine Injection veterinary 10 mg/ml is a muscarinic antagonist that is used to treat poisoning by muscarinic agents, including organophosphates and other drugs. It is also used to treat symptomatic bradycardia in the absence of reversible causes, and for pupil dilation ¹. Atropine is included in the World Health Organization List of Essential Medicines. 

Atropine Injection veterinary 10 mg/ml is a competitive, reversible antagonist of muscarinic receptors that blocks the effects of acetylcholine and other choline esters. It has a variety of therapeutic applications, including pupil dilation and the treatment of anticholinergic poisoning and symptomatic bradycardia in the absence of reversible causes. 

Atropine Injection veterinary 10 mg/ml is relatively inexpensive and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal, and ophthalmic methods. It is generally available as a sulfate salt and oral atropine is only available in combination products.

Indications of Atropine Injection veterinary 10 mg/ml:

For the treatment of muscular spasms as a muscle relaxant and anti-spasm, to decrease secretions of the gastrointestinal and respiratory system, as basic treatment in the cases of poisoning with organic phosphorus compounds in horses, cows, sheep, dogs & cats.
Additional indications
* It is used before anesthesia in surgery to reduce drooling and respiratory secretions.
* This preparation reduces drooling, vomiting, and nausea.
* Atropine Injection veterinary 10 mg/ml is often given with several anesthetic agents to prevent a slow heart rate. It is also used to treat a dangerously slow heart rate and is an important drug in cardiopulmonary resuscitation.
* It is used as a treatment in case of mushroom poisoning.
* It is used for animals that may have difficulty breathing.

Contraindications:

* It should be used with caution in cases of volvulus paralysis, pyloric stenosis, and ulcerative colitis, as it may cause volvulus or a large colon.
* Extreme caution must also be taken in cases of diarrhea and severe myasthenia gravis.
* Atropine Injection veterinary 10 mg/ml should not be used in animals known to be hypersensitive or sensitive to the drug.
* It should also not be used if there is suspected obstruction or infection in the digestive system.
* Do not use if there is inflammation in the large intestine.
*Never give this medication to an animal diagnosed with glaucoma.
* Atropine should be used with caution in animals that have rapid heart rates or if kidney, heart, or liver function is impaired.

Side Effects:

In some special cases, one or more of the following symptoms may appear:
* Dry mouth, difficulty swallowing, thirst, and may cause some animals to drink excess water.
* Dilated pupils, fear of light,
* Transient bradycardia followed by tachycardia with palpitations.
* Difficulty urinating and retention,
* Decrease in intestinal motility, which leads to constipation.
* Drowsiness

Usage and dosage for Atropine Injection veterinary 10 mg/ml:

It is given by subcutaneous injection twice a day on the first day then once a day for week.       
Cats: 0.01 - 0.03 ml.  
Sheep and goats: 0.5 - 3 ml.
Dogs: 0.03 - 0.5 ml.   
Cows and horses: 1.5 - 6 ml.
In the case of poisoning with organic phosphorus compounds give it by intravenous 
 injection: 
Cats and dogs : 0.1 - 0.2 ml/10kg
Cows: 5 - 10 ml /100kg  
Horses: 1 - 2 ml /100kg

Withdrawal Period:

for Meat: 5 days, for milk: 3 days.

Useful Links:

en.wikipedia.org/wiki/Atropine

Composition:

Each 1ml contains:Atropine Sulfate 10  mg